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In
  1844, the first U.S. patent was issued for a printing press with different colors of ink applied in one impression (No. 3,744). The inventor, Thomas F.
  Adams of Philadelphia, Pa., called it "polychrome printing." The
  process used several ink fountains feeding different color rollers which
  operated in parallel on the same axle, to produce stripes of different colors to ink corresponding lines of type. 
 
 
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 Biology |  
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In
  1884, cocaine was first used as a local anaesthetic to immobilize a patient's
  eye for eye surgery by Carl Koller. His success initiated the modern era
  of local anesthesia, with cocaine also quickly adopted for nose and throat
  surgery and for dentistry. For Koller, a Czech-born American ophthalmologist,
  the clue for this use was when he noticed that cocaine had a numbing effect
  on the tongue. He made many experiments on animals before introducing its use
  on humans. Cocaine was isolated in 1859 and was synthesized in 1885. It was
  later found with high doses or repeated use, it caused erosion of the corneal
  epithelium in high doses and it was replaced by less toxic, synthetic local
  anesthetics such as tetracaine and proparacaine. 
 
 
  | 
 Chemistry |  
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In
  1885, a U.S. patent was issued for saccharine, the artificial sweetener
  discover by Constantin Fahlberg (No. 326,281). He had alreaday
  patented the substance "benzoic sulfinide" which he had found
  to be exceptionally sweet tasting (No. 319,082, 2 Jun 1885). In his new
  patent, his invention was to mix a small quantity of this compound with a
  large amount of grape or starch sugar, which he then called
  "dextro-saccharine." In this form, the mixture had, he
  claimed, "the sweetening property of cane sugar, or saccharose, so as to
  be successfully used in the preparation of candies, preserves, cordials,
  &c." He described mixing 2-lb of the chemical compound with
  1-ton of grape sugar, by solution and evaporation. Taking advantage of the
  lower cost of grape sugar, this was cheaper than cane-sugar. |  
 
  | 
 Physics |  
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In
  1898, in a paper dated 1 Sep, Ernest Rutherford coined the
  terms alpha and beta "for two distinct types of
  radiation,.one that is very readily absorbed, which will be termed for
  convenience the α radiation, and the other of a more penetrative character,
  which will be termed the β radiation." His paper, Uranium Radiation
  and the Electrical Conduction Produced by It, gave tables of the amount of
  radiation that passed through successive layers of metal leaf (or aluminium
  foil). He measured it using the rate at which charge leaked off a zinc plate
  due to the ionizing influence of the uranium radiation that reached it, as
  detected by the needle of an electrometer connected to it. He also compared
  the radiation emitted by different uranium compounds; and transparency to the
  radiation of different filter substances. 
 
  | 
 Earth
  Science |  
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In
  1854, the first observation made in North America of a previously unknown
  asteroid was recorded by Scottish-born American James Ferguson of
  the U.S. Naval Observatory. This was the thirty-first of the series and is
  now known as 31 Euphrosyne, named after one of the Charites in Greek
  mythology. It is one of the largest of the main belt asteroids, between Mars
  and Jupiter. Ferguson subsequently discovered two more asteroids: 50 Virginia
  (4 Oct 1857) and 60 Echo (14 Sep 1860). Within the next two decades, more
  asteroids were discovered by American astronomers: one by Searle, two by
  Tuttle (1861-62), 16 by Watson (1863-74), and 22 by Peters (1861-1875),
  making a total of 44 discovered in a period of about 20 years. 
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  | 
 Quote |  
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The significant problems we
  have cannot be solved at the same level of thinking with which we created
  them. - Albert Einstein 
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